We have just released a new protocol  developed in collaboration with scientists at Genentech, to help you bring more biological relevance into your LigandTracer assays.

A simple method to immobilize spheroids using a thin Matrigel coating ready for real-time binding studies in just 3-days.

• Mimics in vivo conditions better than 2D cultures
• Reveals more realistic binding kinetics
• Enables insights into drug penetration and retention

Compared to monolayers, spheroids show slower, more complex binding behavior highlighting effects like tissue penetration.

👉 Access the full protocol Here.

If you would like guidance implementing this method or adapting it to your workflow, feel free to reach out. We are happy to help.